Hormones & Neoplasia
Relationships with neoplasia
- Hormones cause neoplasms
- Tamoxifen: endometrial adenocarcinoma (partial oestrogen agonist)
- Oestrogen causes endometrial cancer
- Methylated steroid hormones cause liver neoplasms
- Hormones treat neoplasms
- Tamoxifen + breast
- Progestogens + endometrial cancer
- Antiandrogens + prostate cancer
- Thyroid cancer with thyroxine
- Neoplasms secrete hormones
- Eutopic (from tumour tissues that normally secrete hormones) - adrenal, ovarian, thyroid, pituitary, kidney
- Ectopic (from tissues that do not normally secrete hormoneS) - carcinoid, neuroendocrine tumours
- Neoplasms may be hormone dependent
- Papillary carcinoma of thyroid
- Breast ca may be dependent on oestrogen
