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Applied Physiology
- Acid-base
- Action potential
- Bile
- Calcium Balance
- Cardiac function
- Coagulation
- Electrocardiography (ECG)
- Fat / Pulmonary Embolus (PE)
- Fluid compartments / fluid balance
- Gastrointestinal physiology
- Liver
- Lung disorders
- Magnesium balance
- Microcirculation
- Motor Control / Muscle contraction
- Neurotransmission and Receptors
- Pancreas / Glucose control
- Postural changes
- Potassium Balance
- Pulse / Blood pressure
- Renal Failure
- Renal function
- Respiratory function
- Sodium balance
- Spleen
- Systemic stress response
- Valsalva
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Spleen
The Spleen

- Size of a cupped hand; lies 9-11 ribs
- Forms left lateral extremity of lesser sac
- Ligaments - gastrosplenic, lienorenal
- Notched: hilum
- Blood supply: splenic artery
Relations
- Posterior: left diaphragm
- anterior: stomach
- Inferior: splenic flexure
- Medially: left kidney
Functions of the spleen
- Filtration - removal of old/abnormal red blood cells, white cells, platelets and cellular debris
- Immunological - produces opsonin, antibody synthesis and protection from infection
- Storage: 35% platelets are stored in spleen
Features in trauma to suspect splenic injury
- Direct blunt trauma
- Guarded tender abdomen
- Low rib fractures (9-11 ribs)
- Shock
- Shoulder tip pain (phrenic nerve)