Effects of tumours
Cachexia (IL1, TNFa related)
Primary / Local effects
- Pressure effects
- Obstruction/compression
- Haemorrhage
- Infection leading to septicaemia
- Infarction (torsion of polyp)
- Pathological fractures
- Biochemical/hormonal abnormalities
Metastatic effects
Paraneoplastic manifestations
- Syndrome in which there are symptoms and signs caused by a neoplasm other than by its direct involvement, metastatic spread
Classification
- Endocrine
- Cushing's syndrome
- ADH secretion
- PTHrP
- Carcinoid syndrome
- Haematological
- Polycythaemia
- DIC
- Thrombocythaemia
- Dermatological
- Acanthosis nigricans
- Dermatomyositis
- Erythema gyratum repens
- Erythroderma
- Clubbing
- Neuromuscular
- Polymyositis
- Myopathies - Myasthenia, GBS
